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DTX4 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - DTX4 Antibody (Internal) ALS17122
    Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9Y2E6
Other Accession 23220
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 67258 Da
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1 - 2 µg/ml),
Additional Information
Gene ID 23220
Other Names DTX4, Deltex homolog 4 (Drosophila), Deltex4, KIAA0937, RNF155, Protein deltex-4, RING finger protein 155, Deltex 4 homolog, Deltex 4 homolog (Drosophila)
Target/Specificity DTX4 antibody is human and mouse reactive. At least two isoforms of DTX4 are known to exist; this antibody will detect both isoforms. DTX4 antibody is predicted to not cross-react with other DTX protein family members.
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsDTX4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DTX4
Synonyms KIAA0937, RNF155
Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

References

Nagase T.,et al.DNA Res. 6:63-70(1999).
Storck S.,et al.Mol. Cell. Biol. 25:1437-1445(2005).
Cui J.,et al.Nat. Immunol. 13:387-395(2012).

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$ 395.00
Cat# ALS17122
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