|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||305011 Da|
|Dilution||IHC-P (10 µg/ml), WB (1 - 2 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||TENM1, Teneurin-1, TNM, ODZ1, ODZ3, TEN-M1, TNM1|
|Target/Specificity||TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TNM / Teneurin-1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer (By similarity).|
|Cellular Location||Cell membrane; Single-pass membrane protein Teneurin C-terminal-associated peptide: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with the dystroglycan complex at the cell membrane in hippocampal cells. Binds hippocampal cell membranes and is incorporated in the cytoplasm by endocytosis in a caveoli-dependent manner. Upon cell internalization is transported arround and in the nucleus (By similarity).|
|Tissue Location||Expressed in fetal brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer (By similarity).
Brandau O.,et al.Hum. Mol. Genet. 8:2407-2413(1999).
Ross M.T.,et al.Nature 434:325-337(2005).
Minet A.D.,et al.J. Cell Sci. 112:2019-2032(1999).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Sjoeblom T.,et al.Science 314:268-274(2006).
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