|Application ||WB, IHC-P|
|Reactivity||Human, Rat, Dog|
|Calculated MW||69285 Da|
|Dilution||IHC-P (1:50), WB (1:2000),|
|Other Names||LTA4H, Leukotriene A(4) hydrolase, Leukotriene A4 hydrolase, Leukotriene A-4 hydrolase, LTA-4 hydrolase, LTA4|
|Target/Specificity||Human LTA4H / LTA4|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||LTA4H / LTA4 Antibody (clone 8F4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.|
|Tissue Location||Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts|
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Provided below are standard protocols that you may find useful for product applications.
Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.
Minami M.,et al.J. Biol. Chem. 262:13873-13876(1987).
Funk C.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6677-6681(1987).
Mancini J.A.,et al.Eur. J. Biochem. 231:65-71(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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