CDK2AP1 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O14519 |
Other Accession | 8099 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 12365 Da |
Dilution | IHC-P (10 µg/ml), |
Gene ID | 8099 |
---|---|
Other Names | CDK2AP1, Doc-1, DORC1, Deleted in oral cancer 1, Deleted in oral cancer-1, p12DOC-1, ST19, CDK2-associated protein 1, CDKAP1, DOC1 |
Target/Specificity | Human DOC-1 / CDK2AP1 |
Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | CDK2AP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDK2AP1 |
---|---|
Synonyms | CDKAP1, DOC1 |
Function | Inhibitor of cyclin-dependent kinase CDK2 (By similarity). Also acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:20523938, PubMed:16428440, PubMed:28977666). |
Cellular Location | Nucleus. Chromosome |
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Provided below are standard protocols that you may find useful for product applications.
Background
specific inhibitor of the cell-cycle kinase CDK2.
References
Daigo Y.,et al.Genes Chromosomes Cancer 20:204-207(1997).
Tsuji T.,et al.J. Biol. Chem. 273:6704-6709(1998).
Arakawa T.,et al.Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Scherer S.E.,et al.Nature 440:346-351(2006).
Ertekin A.,et al.J. Biol. Chem. 287:16541-16549(2012).
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