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TRIP / LRRFIP1 Antibody

Rabbit Polyclonal Antibody

     
  • IHC-P - TRIP / LRRFIP1 Antibody ALS17173
    Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC-P - TRIP / LRRFIP1 Antibody ALS17173
    Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q32MZ4
Other Accession 9208
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 89253 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 9208
Other Names LRRFIP1, FLAP-1, FLAP1, FLIIAP1, GCF2, LRR FLII-interacting protein 1, HUFI-1, Tcf9, Tcf-9, TRIP, NEDD8-conjugating enzyme, TAR RNA-interacting protein, Transcription factor 9, GC-binding factor 2, GCF-2
Reconstitution & Storage PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsTRIP / LRRFIP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRFIP1
Synonyms GCF2, TRIP
Function Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Ubiquitously expressed.
Citations (0)

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Background

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

References

Reed A.L.,et al.J. Biol. Chem. 273:21594-21602(1998).
Wilson S.A.,et al.Nucleic Acids Res. 26:3460-3467(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Fong K.S.K.,et al.Genomics 58:146-157(1999).
Khachigian L.M.,et al.Circ. Res. 84:1258-1267(1999).

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$ 395.00
Cat# ALS17173
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