|Application ||WB, IHC-P|
|Calculated MW||93558 Da|
|Dilution||IHC-P (1:100 - 1:1000),|
|Other Names||AXIN2, AXIL, Axin-2, Axis inhibition protein 2, Axin 2, Axin-like protein, Conductin|
|Target/Specificity||Human AXIN2 / Axin 2|
|Reconstitution & Storage||PBS, pH 7.0, 20% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||AXIN2 / Axin 2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).|
|Tissue Location||Expressed in brain and lymphoblast.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).
Mai M.,et al.Genomics 55:341-344(1999).
Zhang T.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Takahashi M.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Liu W.,et al.Nat. Genet. 26:146-147(2000).
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