|Application ||WB, IHC-P|
|Calculated MW||52071 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:500 - 1:3000),|
|Other Names||PROC, Anticoagulant protein C, Blood coagulation factor XIV, Autoprothrombin IIA, Protein C, PROC1, Vitamin K-dependent protein C, THPH3, THPH4|
|Target/Specificity||Human Protein C|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||PROC / Protein C Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.|
|Tissue Location||Plasma; synthesized in the liver.|
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Provided below are standard protocols that you may find useful for product applications.
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
Beckmann R.J.,et al.Nucleic Acids Res. 13:5233-5247(1985).
Foster D.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:4673-4677(1985).
Plutzky J.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:546-550(1986).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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