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PROC / Protein C Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC-P - PROC / Protein C Antibody (Internal) ALS17197
    Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • WB - PROC / Protein C Antibody (Internal) ALS17197
    Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. Protein C antibody diluted at 1:3000
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P04070
Other Accession 5624
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 52071 Da
Dilution IHC-P (10 µg/ml), WB (1:500 - 1:3000),
Additional Information
Gene ID 5624
Other Names PROC, Anticoagulant protein C, Blood coagulation factor XIV, Autoprothrombin IIA, Protein C, PROC1, Vitamin K-dependent protein C, THPH3, THPH4
Target/Specificity Human Protein C
Reconstitution & Storage 0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsPROC / Protein C Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PROC
Function Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265). Exerts a protective effect on the endothelial cell barrier function (PubMed:25651845).
Cellular Location Secreted. Golgi apparatus. Endoplasmic reticulum
Tissue Location Plasma; synthesized in the liver.
Volume 50 µl
Research Areas
Citations (0)

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Background

Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.

References

Beckmann R.J.,et al.Nucleic Acids Res. 13:5233-5247(1985).
Foster D.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:4673-4677(1985).
Plutzky J.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:546-550(1986).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS17197
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