|Application ||WB, IHC-P|
|Calculated MW||47351 Da|
|Dilution||IHC-P (5 - 10 µg/ml), WB (1:500 - 1:3000),|
|Other Names||NMUR1, G protein-coupled receptor 66, GPR66, FM-3, FM3, G-protein coupled receptor 66, GPC-R, Neuromedin-U receptor 1, NMU-R1, NMU1R, Neuromedin U receptor 1|
|Reconstitution & Storage||PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal. Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.|
|Precautions||NMUR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the neuromedin-U and neuromedin-S neuropeptides.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Raddatz R.,et al.J. Biol. Chem. 275:32452-32459(2000).
Hillier L.W.,et al.Nature 434:724-731(2005).
Tan C.P.,et al.Genomics 52:223-229(1998).
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