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VNN1 Antibody (clone 4E11)

Mouse Monoclonal Antibody

     
  • IHC-P - VNN1 Antibody (clone 4E11) ALS17214
    Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • E - VNN1 Antibody (clone 4E11) ALS17214
    Detection limit for recombinant GST tagged VNN1 is 1 ng/ml as a capture antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O95497
Other Accession 8876
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a,k
Clone Names 4E11
Calculated MW 57012 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 8876
Other Names VNN1, HDLCQ8, Pantetheinase, Pantetheine hydrolase, Vanin-1, Tiff66, Vanin 1, Vannin 1
Target/Specificity Human VNN1
Reconstitution & Storage PBS, pH 7.4. Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsVNN1 Antibody (clone 4E11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VNN1
Function Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.
Volume 50 µl
Research Areas
Citations (0)

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Background

Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.

References

Galland F.,et al.Genomics 53:203-213(1998).
Prehn S.,et al.Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Maras B.,et al.FEBS Lett. 461:149-152(1999).

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$ 395.00
Cat# ALS17214
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