|Application ||IHC-P, E|
|Calculated MW||57012 Da|
|Dilution||IHC-P (10 µg/ml),|
|Other Names||VNN1, HDLCQ8, Pantetheinase, Pantetheine hydrolase, Vanin-1, Tiff66, Vanin 1, Vannin 1|
|Reconstitution & Storage||PBS, pH 7.4. Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||VNN1 Antibody (clone 4E11) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.|
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Provided below are standard protocols that you may find useful for product applications.
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.
Galland F.,et al.Genomics 53:203-213(1998).
Prehn S.,et al.Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Maras B.,et al.FEBS Lett. 461:149-152(1999).
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