Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RNASE3 Antibody (aa102-151)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P12724 |
| Other Accession | 6037 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 18385 Da |
| Dilution | ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 6037 |
|---|---|
| Other Names | RNASE3, ECP, Ribonuclease 3, RNase 3, Cytotoxic ribonuclease, Eosinophil cationic protein, RNS3 |
| Target/Specificity | ECP antibody detects endogenous levels of ECP. |
| Reconstitution & Storage | PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C. |
| Precautions | RNASE3 Antibody (aa102-151) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RNASE3 |
|---|---|
| Synonyms | ECP, RNS3 |
| Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
| Cellular Location | Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
References
Rosenberg H.F.,et al.J. Exp. Med. 170:163-176(1989).
Hamann K.J.,et al.Genomics 7:535-546(1990).
Barker R.L.,et al.J. Immunol. 143:952-955(1989).
Simonsen C.C.,et al.Submitted (OCT-1990) to the EMBL/GenBank/DDBJ databases.
Zhang J.,et al.Genetics 156:1949-1958(2000).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
