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>   home   >   Products   >   Primary Antibodies   >   RNASE3 Antibody (aa102-151)   

RNASE3 Antibody (aa102-151)

Rabbit Polyclonal Antibody

     
  • IHC-P - RNASE3 Antibody (aa102-151) ALS17215
    Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC-P - RNASE3 Antibody (aa102-151) ALS17215
    Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • WB - RNASE3 Antibody (aa102-151) ALS17215
    Western blot of ECP antibody in extracts from 293 cells.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P12724
Other Accession 6037
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 18385 Da
Dilution ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 6037
Other Names RNASE3, ECP, Ribonuclease 3, RNase 3, Cytotoxic ribonuclease, Eosinophil cationic protein, RNS3
Target/Specificity ECP antibody detects endogenous levels of ECP.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsRNASE3 Antibody (aa102-151) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNASE3
Synonyms ECP, RNS3
Function Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Cellular Location Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus
Volume 50 µl
Citations (0)

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Background

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

References

Rosenberg H.F.,et al.J. Exp. Med. 170:163-176(1989).
Hamann K.J.,et al.Genomics 7:535-546(1990).
Barker R.L.,et al.J. Immunol. 143:952-955(1989).
Simonsen C.C.,et al.Submitted (OCT-1990) to the EMBL/GenBank/DDBJ databases.
Zhang J.,et al.Genetics 156:1949-1958(2000).

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$ 395.00
Cat# ALS17215
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