|Application ||WB, IHC-P|
|Calculated MW||39518 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:2000),|
|Other Names||LGALS9, Gal-9, HUAT, Galectin 9, Galectin-9, LGALS9A, Tumor antigen HOM-HD-21, Ecalectin|
|Target/Specificity||Human LGALS9 / Galectin 9|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||LGALS9 / Galectin 9 Antibody (clone 1G3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.|
|Cellular Location||Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway.|
|Tissue Location||Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue|
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Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.
Tuereci O.,et al.J. Biol. Chem. 272:6416-6422(1997).
Kato S.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Matsumoto R.,et al.J. Biol. Chem. 273:16976-16984(1998).
Nakajima H.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Akiyama S.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
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