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CNP / CNPase Antibody

Rabbit Polyclonal Antibody

     
  • IHC-P - CNP / CNPase Antibody ALS17238
    Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • IHC-P - CNP / CNPase Antibody ALS17238
    Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • WB - CNP / CNPase Antibody ALS17238
    Western blot analysis of extracts of various cell lines, using CNP antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P09543
Other Accession 1267
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 47579 Da
Dilution IHC-P (5 µg/ml), WB (1:500 - 1:2000),
Additional Information
Gene ID 1267
Other Names CNP, CNP1, CNPase, Phosphodiesterase CNP
Target/Specificity Human CNP / CNPase
Reconstitution & Storage PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
PrecautionsCNP / CNPase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNP (HGNC:2158)
Function Catalyzes the formation of 2'-nucleotide products from 2',3'- cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P16330}; Lipid- anchor {ECO:0000250|UniProtKB:P16330}. Melanosome. Note=Firmly bound to membrane structures of brain white matter. {ECO:0000250|UniProtKB:P16330}
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

References

Thompson R.J.,et al.Biochem. Soc. Trans. 20:621-626(1992).
Kurihara T.,et al.Biochem. Biophys. Res. Commun. 152:837-842(1988).
Monoh K.,et al.Gene 129:297-301(1993).
Douglas A.J.,et al.Ann. Hum. Genet. 56:243-254(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 467.50
Cat# ALS17238
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