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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   PRG2 / Proteoglycan 2 Antibody   

PRG2 / Proteoglycan 2 Antibody

Rabbit Polyclonal Antibody

     
  • IHC-P - PRG2 / Proteoglycan 2 Antibody ALS17244
    Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • WB - PRG2 / Proteoglycan 2 Antibody ALS17244
    Western blot analysis of extracts of various cell lines, using PRG2 antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P13727
Other Accession 5553
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 25206 Da
Dilution IHC-P (5 µg/ml), WB (1:500 - 1:2000),
Additional Information
Gene ID 5553
Other Names PRG2, BMPG, Bone marrow proteoglycan, Bone-marrow proteoglycan, Eosinophil major basic protein, MBP1, Natural killer cell activator, Proteoglycan 2, Proteoglycan 2 preproprotein
Target/Specificity Human PRG2 / Proteoglycan 2
Reconstitution & Storage PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
PrecautionsPRG2 / Proteoglycan 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRG2
Synonyms MBP
Function Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
Cellular Location Bone marrow proteoglycan: Secreted. Note=The proform is secreted
Tissue Location High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
Volume 50 µl
Research Areas
Citations (0)

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Background

Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.

References

Barker R.L.,et al.J. Exp. Med. 168:1493-1498(1988).
Barker R.L.,et al.Submitted (OCT-1989) to the EMBL/GenBank/DDBJ databases.
Barker R.L.,et al.Gene 86:285-289(1990).
McGrogan M.,et al.J. Exp. Med. 168:2295-2308(1988).
Yoshimatsu K.,et al.Mol. Immunol. 29:537-546(1992).

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$ 395.00
Cat# ALS17244
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