|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||75679 Da|
|Dilution||IHC-P (5 µg/ml), WB (1:500 - 1:2000),|
|Other Names||ABCG8, Sterolin-2, STSL, GBD4, Sterolin 2|
|Reconstitution & Storage||PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||ABCG8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Strongly expressed in the liver, lower levels in the small intestine and colon. Detectable in a wide variety of human tissues|
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Provided below are standard protocols that you may find useful for product applications.
Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
Berge K.E.,et al.Science 290:1771-1775(2000).
Lu K.,et al.Am. J. Hum. Genet. 69:278-290(2001).
Hillier L.W.,et al.Nature 434:724-731(2005).
Schmitz G.,et al.J. Lipid Res. 42:1513-1520(2001).
Hubacek J.A.,et al.Hum. Mutat. 18:359-360(2001).
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