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Anti-COL17A1 / Collagen XVII Antibody

Rabbit Anti Human Polyclonal Antibody

     
  • IHC-P - Anti-COL17A1 / Collagen XVII Antibody  ALS17278
    Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UMD9
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 150419 Da
Dilution ELISA, IHC-P (10 µg/ml), WB
Additional Information
Gene ID 1308
Alias Symbol COL17A1
Other Names COL17A1, Alpha 1 type XVII collagen, BA16H23.2, BP180, Bullous pemphigoid antigen 2, BPA-2, BPAG2, Collagen alpha-1(XVII) chain, Collagen, type XVII, alpha 1, Lad-1
Target/Specificity Human COL17A1 / Collagen XVII.
Reconstitution & Storage PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsAnti-COL17A1 / Collagen XVII Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL17A1
Synonyms BP180, BPAG2
Function May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
Cellular Location Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome [97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane Note=Localized in the lamina lucida beneath the hemidesmosomes
Tissue Location Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves
Research Areas
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Discontinued
Cat# ALS17278
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