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Anti-SKAP1 / SCAP1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q86WV1 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 41432 Da |
| Dilution | ELISA, IHC-P (10 µg/ml), WB |
| Gene ID | 8631 |
|---|---|
| Alias Symbol | SKAP1 |
| Other Names | SKAP1, Pp55, SKAP55, SKAP-55, SCAP1 |
| Target/Specificity | Human SKAP1 / SCAP1 |
| Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Anti-SKAP1 / SCAP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SKAP1 |
|---|---|
| Synonyms | SCAP1, SKAP55 |
| Function | Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T- cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. |
| Cellular Location | Cytoplasm. Nucleus. Cell membrane. Note=Upon T- cell stimulation, translocates to lipid rafts at the cell membrane |
| Tissue Location | Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells and testis. Present in T- cells (at protein level). |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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