|Application ||WB, IHC-P, E|
|Calculated MW||187148 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB|
|Other Names||C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3|
|Target/Specificity||Human Complement C3|
|Reconstitution & Storage||PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Anti-Complement C3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation.|
|Tissue Location||Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods|
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