Anti-EFTU / TUFM Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P49411 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 49875 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 7284 |
---|---|
Alias Symbol | TUFM |
Other Names | TUFM, EF-TuMT, EF-Tu, EFTU, p43, COXPD4 |
Target/Specificity | Human EFTU / TUFM |
Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | Anti-EFTU / TUFM Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TUFM |
---|---|
Function | Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy. |
Cellular Location | Mitochondrion. |
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