|Application ||WB, IHC-P|
|Calculated MW||13894 Da|
|Dilution||IHC-P (1:200), WB (1:500 - 1:2000)|
|Other Names||PPBP, Beta-thromboglobulin, B-TG1, Beta-TG, C-X-C motif chemokine 7, CTAP3, CXCL7, CTAP-III, CXC chemokine ligand 7, NAP-2, NAP-2-L1, PBP, LA-PF4, LDGF, SCYB7, Small-inducible cytokine B7, Small inducible cytokine B7, THBGB1, Thrombocidin 2, TC2, TGB ...|
|Target/Specificity||Human PPBP / CXCL7|
|Reconstitution & Storage||PBS, 0.1% sodium azide, 50% glycerol Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||Anti-CXCL7 / PPBP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CTAP3, CXCL7, SCYB7, TGB1, THBGB1|
|Function||LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.|
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