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Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus)

Rabbit Anti Human Polyclonal Antibody

  • IHC-P - Anti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus)  ALS17312
    Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35354
Predicted Human, Mouse, Rat, Pig, Sheep, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 68996 Da
Dilution ICC (1:100 - 1:500), IF, IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Gene ID 5743
Alias Symbol PTGS2
Other Names PTGS2, COX-2, Cyclooxygenase-2, COX2, Cyclooxygenase 2b, HCox-2, GRIPGHS, PGH synthase 2, PGHS-2, PHS II, PHS-2, Prostaglandin H2 synthase 2, PGG/HS, Prostaglandin G/H synthase 2
Target/Specificity Recognizes endogenous levels of PGHS-2 protein.
Reconstitution & Storage PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsAnti-PTGS2 / COX2 / COX-2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGS2
Synonyms COX2
Function Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Cellular Location Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein
Research Areas
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$ 395.00
Cat# ALS17312
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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