|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||150701 Da|
|Dilution||IHC-P (1:200), WB (1:500 - 1:1000)|
|Other Names||ADCY9, Adenylate cyclase type 9, Adenylyl cyclase 9, Adenylate cyclase 9, AC9, Adenylate cyclase type IX, KIAA0520, ATP pyrophosphate-lyase 9|
|Target/Specificity||Human ADCY9 / Adenylate Cyclase 9|
|Reconstitution & Storage||PBS, 0.1% sodium azide, 50% glycerol. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||Anti-ADCY9 / Adenylate Cyclase 9 Antibody (aa984-1029) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein- coupled receptors (PubMed:9628827, PubMed:12972952, PubMed:15879435, PubMed:10987815). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta (PubMed:9628827, PubMed:10987815). Expressed in multiple cells of the lung, with expression highest in airway smooth muscle (PubMed:12972952)|
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