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Anti-APOA1 / Apolipoprotein A 1 Antibody
Mouse Anti Human Monoclonal Antibody
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- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P02647 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Calculated MW | 30778 Da |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 335 |
|---|---|
| Alias Symbol | APOA1 |
| Other Names | APOA1, ApoA-I, APOAI, Apolipoprotein A-I, Apolipoprotein A1, Apo-AI |
| Target/Specificity | Specific for ApoA1, No cross reaction to Apo AII or Apo B |
| Reconstitution & Storage | 15mM Potassium Phosphate, 0.85% Sodium Chloride, pH 7.5, 0.1% NaN3 Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | Anti-APOA1 / Apolipoprotein A 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | APOA1 |
|---|---|
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Cellular Location | Secreted. |
| Tissue Location | Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease. |
Research Areas
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$ 395.00
Cat# ALS17317
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