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Anti-MLZE Antibody (aa109-158)

Rabbit Anti Human Polyclonal Antibody

     
  • IHC-P - Anti-MLZE Antibody (aa109-158)  ALS17321
    Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC-P - Anti-MLZE Antibody (aa109-158)  ALS17321
    Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BYG8
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 57692 Da
Dilution ELISA, IHC-P (1:200), WB
Additional Information
Gene ID 56169
Alias Symbol GSDMC
Other Names GSDMC, Gasdermin C, MLZE, Gasdermin-C
Target/Specificity GSDMC Antibody detects endogenous levels of GSDMC.
Reconstitution & Storage PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.
PrecautionsAnti-MLZE Antibody (aa109-158) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSDMC
Synonyms MLZE
Function The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable).
Cellular Location Cytoplasm, cytosol. Cell membrane {ECO:0000250|UniProtKB:P57764}
Tissue Location Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310)
Research Areas
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$ 395.00
Cat# ALS17321
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