|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||47949 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (1:200), WB (1:500 - 1:1000)|
|Other Names||KCNJ16, BIR9, KIR5.1|
|Target/Specificity||Human KCNJ16 / Kir5.1|
|Reconstitution & Storage||PBS, pH 7.2, 0.05% sodium azide Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||Anti-KCNJ16 / Kir5.1 Antibody (aa376-428) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in kidney, pancreas and thyroid gland|
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