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Anti-HP / Haptoglobin Antibody

Goat Anti Human Polyclonal Antibody

     
  • IHC-P - Anti-HP / Haptoglobin Antibody  ALS17332
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP, ID, FC
Primary Accession P00738
Predicted Human
Host Goat
Clonality Polyclonal
Calculated MW 45205 Da
Dilution ELISA, Flo, ID, IHC-P (5 µg/ml), IP, WB
Additional Information
Gene ID 3240
Alias Symbol HP
Other Names HP, Binding peptide, Haptoglobin alpha(1S)-beta, Haptoglobin, beta polypeptide, Haptoglobin, Haptoglobin alpha(2FS)-beta, Haptoglobin, alpha polypeptide, HP2ALPHA2, BP, Zonulin, HPA1S
Target/Specificity Human Haptoglobin
Reconstitution & Storage 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2, 0.05% sodium azide. Store at 2-8°C
PrecautionsAnti-HP / Haptoglobin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HP
Function As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)
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$ 467.50
Cat# ALS17332
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