Anti-ESPL1 / Separase Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC, IP |
---|---|
Primary Accession | Q14674 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 233175 Da |
Dilution | ICC, IHC-P (5 µg/ml), IP, WB |
Gene ID | 9700 |
---|---|
Alias Symbol | ESPL1 |
Other Names | ESPL1, ESP1, Extra spindle poles like 1, KIAA0165, Caspase-like protein ESPL1, SEPA, Separase, Separin |
Target/Specificity | Recognizes human Separase. |
Reconstitution & Storage | TBS, pH 7.2, 0.1% BSA, 0.05% sodium azide Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | Anti-ESPL1 / Separase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ESPL1 |
---|---|
Synonyms | ESP1, KIAA0165 |
Function | Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. |
Cellular Location | Cytoplasm. Nucleus. |
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