|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||28219 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (1:200), WB (1:500 - 1:1000)|
|Other Names||YWHAH, 14-3-3 eta, 14-3-3 protein eta, Protein AS1, YWHA1|
|Target/Specificity||Human 14-3-3 Eta / YWHAH|
|Reconstitution & Storage||PBS, pH 7.2, 0.05% sodium azide Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||Anti-YWHAH / 14-3-3 Eta Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.|
|Tissue Location||Expressed mainly in the brain and present in other tissues albeit at lower levels|
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