|Calculated MW||27807 Da|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||PRTN3, ACPA, Azurophil granule protein 7, C-ANCA antigen, CANCA, C-ANCA, AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, NP4, p29, PR-3, Proteinase 3, MBT, Wegener autoantigen, PR3, Serine proteinase, neutrophil|
|Target/Specificity||Human PRTN3 / Proteinase 3|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide Store at -20°C. Minimize freezing and thawing.|
|Precautions||Anti-PRTN3 / Myeloblastin Antibody (aa28-248, clone 5B8) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.|
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