|Application ||WB, IHC-P, IF|
|Predicted||Human, Mouse, Rat|
|Calculated MW||50408 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (1:100), WB (1:500 - 1:2000)|
|Other Names||ETS1, Ets protein, ETS-1, EWSR2, p54, Protein C-ets-1|
|Reconstitution & Storage||PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.|
|Precautions||Anti-ETS1 / ETS-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.|
|Cellular Location||Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27|
|Tissue Location||Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.|
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