|Application ||WB, IHC-P|
|Calculated MW||39439 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:2000)|
|Other Names||P2RY12, ADP-glucose receptor, ADPG-R, p2Y(12)R, p2Y(ADP), p2T(AC), p2Y12, Platelet ADP receptor, SP1999, p2RY12, p2Y purinoceptor 12, Purinergic receptor P2RY12, BDPLT8, Gi-coupled ADP receptor HORK3, HORK3, p2Y(AC), p2Y(cyc), p2Y12 platelet ADP receptor|
|Target/Specificity||Human P2RY12 / P2Y12|
|Reconstitution & Storage||PBS, pH 7.4, 0.05% sodium azide. Store at 4°C for up to 1 year. Avoid repeated freezing and thawing.|
|Precautions||Anti-P2RY12 / P2Y12 Antibody (aa324-342) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.|
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