Anti-P2RY12 / P2Y12 Antibody (aa324-342)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9H244 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 39439 Da |
Dilution | IHC-P (1:100), WB (1:500 - 1:2000) |
Gene ID | 64805 |
---|---|
Alias Symbol | P2RY12 |
Other Names | P2RY12, ADP-glucose receptor, ADPG-R, p2Y(12)R, p2Y(ADP), p2T(AC), p2Y12, Platelet ADP receptor, SP1999, p2RY12, p2Y purinoceptor 12, Purinergic receptor P2RY12, BDPLT8, Gi-coupled ADP receptor HORK3, HORK3, p2Y(AC), p2Y(cyc), p2Y12 platelet ADP receptor |
Target/Specificity | Human P2RY12 / P2Y12 |
Reconstitution & Storage | PBS, pH 7.4, 0.05% sodium azide. Store at 4°C for up to 1 year. Avoid repeated freezing and thawing. |
Precautions | Anti-P2RY12 / P2Y12 Antibody (aa324-342) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | P2RY12 |
---|---|
Synonyms | HORK3 |
Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain |
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