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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC10)
Anti-KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC10)
Mouse Anti Human Monoclonal Antibody
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Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P05783 |
| Predicted | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1,k |
| Clone Names | DC10 |
| Calculated MW | 48058 Da |
| Dilution | IHC-P (10 µg/ml), WB |
| Gene ID | 3875 |
|---|---|
| Alias Symbol | KRT18 |
| Other Names | KRT18, CK-18, Cytokeratin 18, Cytokeratin-18, K18, Keratin 18, CYK18, Keratin-18 |
| Target/Specificity | Human KRT18 / CK18 / Cytokeratin 18 |
| Reconstitution & Storage | PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Precautions | Anti-KRT18 / CK18 / Cytokeratin 18 Antibody (clone DC10) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT18 |
|---|---|
| Synonyms | CYK18 |
| Function | Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
| Cellular Location | Nucleus matrix {ECO:0000250|UniProtKB:Q5BJY9}. Cytoplasm, perinuclear region. Nucleus, nucleolus. Cytoplasm {ECO:0000250|UniProtKB:Q5BJY9} |
| Tissue Location | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS17388
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