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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-MITF Antibody (aa150-427, clone ABM1H91)    

Anti-MITF Antibody (aa150-427, clone ABM1H91)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75030
Predicted Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names ABM1H91
Calculated MW 58795 Da
Dilution IHC-P (10 µg/ml), WB
Additional Information
Gene ID 4286
Alias Symbol MITF
Other Names MITF, BHLHe32, CMM8, MI, Waardenburg syndrome, type 2A, WS2, WS2A
Reconstitution & Storage PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsAnti-MITF Antibody (aa150-427, clone ABM1H91) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BHLHE32
Function Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Cellular Location Nucleus.
Tissue Location Isoform M is exclusively expressed in melanocytes and melanoma cells. Isoform A and isoform H are widely expressed in many cell types including melanocytes and retinal pigment epithelium (RPE). Isoform C is expressed in many cell types including RPE but not in melanocyte-lineage cells. Isoform Mdel is widely expressed in melanocytes, melanoma cell lines and tissues, but almost undetectable in non-melanoma cell lines
Research Areas
Citations (0)

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$ 395.00
Cat# ALS17391
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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