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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-TRIM29 Antibody (aa4-129)
Anti-TRIM29 Antibody (aa4-129)
Rabbit Anti Human Polyclonal Antibody
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- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q14134 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65835 Da |
| Dilution | IHC-P (5 µg/ml), WB |
| Gene ID | 23650 |
|---|---|
| Alias Symbol | TRIM29 |
| Other Names | TRIM29, ATDC, Tripartite motif containing 29, Tripartite motif-containing 29 |
| Target/Specificity | Human TRIM29 |
| Reconstitution & Storage | PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Precautions | Anti-TRIM29 Antibody (aa4-129) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRIM29 |
|---|---|
| Synonyms | ATDC |
| Function | Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. |
| Cellular Location | Cytoplasm. Lysosome. Note=Colocalizes with intermediate filaments |
| Tissue Location | Expressed in placenta, prostate and thymus. |
Research Areas
Citations (0)
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Application Protocols
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$ 467.50
Cat# ALS17395
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