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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-CYP4Z1 Antibody (Internal)
Anti-CYP4Z1 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q86W10 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59086 Da |
| Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
| Gene ID | 199974 |
|---|---|
| Alias Symbol | CYP4Z1 |
| Other Names | CYP4Z1, Cytochrome P450 4Z1, CYP4A20, CYPIVZ1 |
| Target/Specificity | Recognizes endogenous levels of Cytochrome P450 4Z1/2 protein. |
| Reconstitution & Storage | PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
| Precautions | Anti-CYP4Z1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CYP4Z1 {ECO:0000303|PubMed:19090726, ECO:0000312|HGNC:HGNC:20583} |
|---|---|
| Function | A cytochrome P450 monooxygenase that catalyzes the in-chain oxidation of fatty acids (PubMed:19090726, PubMed:29018033). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates lauric and myristic acids predominantly at the omega-4 and omega-2 positions, respectively (PubMed:19090726, PubMed:29018033). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Displays an absolute stereoselectivity in the epoxidation of arachidonic acid producing the 14(S),15(R)-epoxyeicosatrienoic acid (EET) enantiomer (PubMed:29018033). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:19090726, PubMed:29018033). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein |
| Tissue Location | Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues. |
Research Areas
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Application Protocols
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Discontinued
Cat# ALS17415
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