Anti-CLK4 Antibody (aa70-150)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9HAZ1 |
Predicted | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 57492 Da |
Dilution | ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:2000) |
Gene ID | 57396 |
---|---|
Alias Symbol | CLK4 |
Other Names | CLK4, CDC-like kinase 4 |
Target/Specificity | CLK4 Polyclonal Antibody detects endogenous levels of CLK4 protein. |
Reconstitution & Storage | PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol. Store at -20°C. Avoid freeze/thaw cycles. |
Precautions | Anti-CLK4 Antibody (aa70-150) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CLK4 |
---|---|
Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in liver, kidney, heart, muscle, brain and endothelial cells. |
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