|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Monkey|
|Calculated MW||34062 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||SLC25A11, OGC, SLC20A4, OGCP, Oxoglutarate carrier, Oxoglutarate translocator, Oxoglutarate/malate carrier|
|Target/Specificity||Recognizes endogenous levels of SLC25A11 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-SLC25A11 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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