|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||50708 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||RTN4R, Nogo receptor, Nogo-66 receptor, Reticulon-4 receptor, NGR, NOGO-A, UNQ330/PRO526, NOGOR, Reticulon 4 receptor|
|Target/Specificity||Recognizes endogenous levels of RTN4R protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-NOGO-A / RTN4R Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity).|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
|Tissue Location||Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter)|
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