|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||113824 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||DSG4, Cadherin family member 13, CDGF13, CDH family member 13, Desmoglein 4, Desmoglein-4, LAH, CDHF13|
|Target/Specificity||Recognizes endogenous levels of Desmoglein 4 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-DSG4 / Desmoglein 4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome|
|Tissue Location||Highly expressed in skin, testis and prostate; less in salivary gland. In scalp follicles, present in the inner root sheath (IRS) and all layers of the matrix and precortex|
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