|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||7038 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||DEFB4A, Beta-defensin 2, Beta-defensin 4A, DEFB-2, DEFB102, Defensin, beta 2, Defensin, beta 4, Defensin, beta 4A, DEFB4, DEFB2, HBD-2, Skin-antimicrobial peptide 1, BD-2, SAP1|
|Target/Specificity||Recognizes endogenous levels of Defensin beta 2 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-DEFB4A / BD-2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||DEFB102, DEFB2, DEFB4|
|Function||Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).|
|Tissue Location||Expressed in the skin and respiratory tract.|
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