|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||24803 Da|
|Dilution||ELISA (0.05 - 0.2 µg/ml), IHC-P (10 µg/ml), WB (0.5 - 1 µg/ml)|
|Other Names||GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1|
|Target/Specificity||Endogenous levels of mouse and rat GAP-43. It is predicted to react with human GAP-43 according to sequence homology. Positive Control: Mouse brain and rat brain lysates.|
|Reconstitution & Storage||Lyophilized from PBS, pH 7.4, 0.02% sodium azide. Store lyophilized at -20°C. The reconstituted product can be stored for short term at 4 °C or long term at -20 °C or below. Avoid freeze/thaw cycles.|
|Precautions||Anti-GAP43 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes|
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