|Application ||IHC-P, ICC|
|Calculated MW||34072 Da|
|Dilution||ICC, IHC-P (5 - 9 µg/ml)|
|Other Names||GPR35, KYNA receptor, Kynurenic acid receptor, G protein-coupled receptor 35, G-protein coupled receptor 35|
|Target/Specificity||Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-GPR35 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Internalized to the cytoplasm after exposure to kynurenic acid|
|Tissue Location||Predominantly expressed in immune and gastrointestinal tissues.|
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