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Anti-GPR62 Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9BZJ7 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37614 Da |
| Dilution | IHC-P (4 µg/ml) |
| Gene ID | 118442 |
|---|---|
| Alias Symbol | GPR62 |
| Other Names | GPR62, G protein-coupled receptor 62, GPCR8, KPG_005, HGPCR8 |
| Target/Specificity | Human GPR62. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-GPR62 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR62 |
|---|---|
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2 in the endosome (PubMed:28827538). |
| Tissue Location | Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus |
Research Areas
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$ 467.50
Cat# ALS17478
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