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Anti-HRH3 / Histamine 3 Receptor Antibody (Cytoplasmic Domain)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5N1
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 48671 Da
Dilution IHC-P (2 - 8 µg/ml), WB
Additional Information
Gene ID 11255
Alias Symbol HRH3
Other Names HRH3, G protein-coupled receptor 97, GPCR97, H3 histamine receptor, H3R, HH3R, Histamine H3 receptor, Histamine receptor H3, G-protein coupled receptor 97, Histamine 3 receptor
Target/Specificity Human HRH3 / Histamine H3 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-HRH3 / Histamine 3 Receptor Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HRH3
Synonyms GPCR97
Function The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra
Research Areas
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$ 395.00
Cat# ALS17479
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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