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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-GPR173 / SREB3 Antibody (Transmembrane Domain)
Anti-GPR173 / SREB3 Antibody (Transmembrane Domain)
Rabbit Anti Human Polyclonal Antibody
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- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9NS66 |
| Predicted | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41481 Da |
| Dilution | IHC-P (2 µg/ml) |
| Gene ID | 54328 |
|---|---|
| Alias Symbol | GPR173 |
| Other Names | GPR173, G protein coupled receptor 173, G-protein coupled receptor 173, G protein-coupled receptor 173, SREB3 |
| Target/Specificity | Human GPR173. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-GPR173 / SREB3 Antibody (Transmembrane Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR173 |
|---|---|
| Synonyms | SREB3 |
| Function | Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth (PubMed:30933929). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level) (PubMed:30933929). Expressed at high levels in brain. Lower levels in small intestine. In brain regions, detected in all regions tested. Highest levels in the cerebellum and cerebral cortex. |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS17483
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