Anti-NR2E3 / PNR Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q9Y5X4 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 44692 Da |
Dilution | IHC-P (7 µg/ml) |
Gene ID | 10002 |
---|---|
Alias Symbol | NR2E3 |
Other Names | NR2E3, ESCS, PNR, RNR, Rd7, RP37 |
Target/Specificity | Human NR2E3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-NR2E3 / PNR Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NR2E3 |
---|---|
Synonyms | PNR, RNR |
Function | Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:15689355} |
Tissue Location | Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside. |
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