|Calculated MW||51547 Da|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||VIPR1, HVR1, PACAP type II receptor, PACAP-R-2, Pvr2, RDC1, Vip receptor subtype 1, Vpac1 receptor, V1RG, VIP receptor 1, VIPR, VIRG, VPCAP1R, PACAP-R2, VAPC1, VIP and PACAP receptor 1, VPAC1R, Pacap receptor, type ii, Type II PACAP receptor, VIP rec ...|
|Target/Specificity||Human VIP Receptor 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-VIPR1 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT.|
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