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Anti-GPBAR1 / TGR5 Antibody (Cytoplasmic Domain)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q8TDU6
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 35248 Da
Dilution IHC-P (18 µg/ml)
Additional Information
Gene ID 151306
Alias Symbol GPBAR1
Other Names GPBAR1, BG37, GPR131, HGPCR19, M-BAR, GPCR19, TGR5, GPCR TGR5, HBG37, Membrane bile acid receptor
Target/Specificity Human TGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-GPBAR1 / TGR5 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPBAR1
Synonyms TGR5
Function Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum
Research Areas
Citations (0)
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Discontinued
Cat# ALS17508
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