Anti-HRH2 / Histamine H2 Receptor Antibody (Extracellular Domain)
Rabbit Anti Human Polyclonal Antibody
|Calculated MW||40098 Da|
|Dilution||IHC-P (18 µg/ml)|
|Other Names||HRH2, Gastric receptor I, H2R, Histamine 2 receptor, Gastric receptor 1, H2 histamine receptor, HH2R, Histamine type 2 receptor, Histamine H2 receptor, Histamine receptor H2|
|Target/Specificity||Human HRH2 / Histamine H2 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-HRH2 / Histamine H2 Receptor Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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