|Predicted||Human, Rat, Rabbit, Hamster, Monkey, Horse, Guinea Pig|
|Calculated MW||46251 Da|
|Dilution||IHC-P (1 - 40 µg/ml)|
|Other Names||TACR1, Neurokinin receptor 1, NK-1R, Nk1 tachykinin receptor, NK1R, TAC1R, Tachykinin 1 receptor, NKIR, Substance-P receptor, Neurokinin 1 receptor, NK-1 receptor, Tachykinin receptor 1|
|Target/Specificity||Human Neurokinin 1 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DTNB (44%).|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-TACR1 / NK1R Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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