|Calculated MW||47441 Da|
|Dilution||IHC-P (7.2 µg/ml)|
|Other Names||F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1|
|Target/Specificity||Human Thrombin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRIN1 (47%).|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-F2R / Thrombin Receptor / PAR1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CF2R, PAR1, TR|
|Function||High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Platelets and vascular endothelial cells.|
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